Genetics & Developmental Biology Stories
Baltimore MD— We would not expect a baby to join a team or participate in social situations that require sophisticated communication. Yet, most developmental biologists have assumed that young cells...
Tuesday, November 25, 2014, Baltimore, MD—Biologist Marnie Halpern of Carnegie’s Department of Embryology has been named a Fellow of the American Association for the Advancement of Science (AAAS) for...
In mammals, most lipids, such as fatty acids and cholesterol, are absorbed into the body via the small intestine. The complexity of the cells and fluids that inhabit this organ make it very...
As animals age, their immune systems gradually deteriorate, a process called immunosenescence. It is associated with systemic inflammation and chronic inflammatory disorders, as well as with many...
Baltimore, MD—As animals age, their immune systems gradually deteriorate, a process called immunosenescence. It is associated with systemic inflammation and chronic inflammatory disorders, as well as...
The hypothalamus is an essential brain center that maintains multiple physiological homeostatic processes by modulating pituitary hormone secretions. Two centers (nuclei) of the hypothalamus, the...
September 16, 2014
Speaker: Dr. Matthew P. Scott
Why do we look like our parents? We inherit particular versions of genes that shape our growth. For a long time these genes were unknown and it was...
Baltimore, MD--The General Motors Corporation is presenting a $5,000.00 award to Carnegie’s BioEYES K-12 educational program on September 11, 2014, to deliver a two-week environmental curriculum,...
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The Fan laboratory studies the molecular mechanisms that govern mammalian development, using the mouse as a model. They use a combination of biochemical, molecular and genetic approaches to identify and characterize signaling molecules and pathways that control the development and maintenance of...
The Marnie Halpern laboratory studies how left-right differences arise in the developing brain and discovers the genes that control this asymmetry. Using the tiny zebrafish, Danio rerio, they explores how regional specializations occur within the neural tube, the embryonic tissue that develops into...
The Spradling laboratory studies the biology of reproduction. By unknown means eggs reset the normally irreversible processes of differentiation and aging. The fruit fly Drosophila provides a favorable multicellular system for molecular genetic studies. The lab focuses on several aspects of egg...
Junior investigator Zhao Zhang joined Carnegie in November 2014. He studies how elements with the ability to “jump” around the genome, called transposons, are controlled in egg, sperm, and other somatic tissues in order to understand how transposons contribute to genomic instability and to...
In mammals, most lipids, such as fatty acids and cholesterol, are absorbed into the body via the small intestine. The complexity of the cells and fluids that inhabit this organ make it very difficult to study in a laboratory setting. The goal of the Farber lab is to better understand the cell and...
The mouse is a traditional model organism for understanding physiological processes in humans. Chen-Ming Fan uses the mouse to study the underlying mechanisms involved in human development and genetic diseases. He concentrates on identifying and understanding the signals that direct the...
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Baltimore, MD — Insect glands are responsible for producing a host of secretions that allow bees to sting and ants to lay down trails to and from their nests. New research from Carnegie scientists...
Using the CRISPR/Cas9 genome-editing tool, biologists can now target specific genes for mutation and then see how this induced mutation manifests in an organism. But sometimes an organism compensates...
New work led by Carnegie’s Steven Farber, with help from Yixian Zheng’s lab, sheds light on how form follows function for intestinal cells responding to high-fat foods that are rich in cholesterol...
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