Genetics & Developmental Biology Stories
Baltimore, MD—Carnegie’s BioEYES K-12 science educational program launches a new center sponsored by the University of Utah, Department of Pediatrics, Pediatric Research Enterprise. The...
Allan Spradling offers input to The Scientist on a paper about female Japanese rice fish producing sperm....
Dr. Matthew P. Scott
President,
Carnegie Institution for Science
Carnegie Astronomy is also part of Carnegie Science and the study of all living species. From ancient single-celled organisms evolved...
A Carnegie Evening Lecture
Dr. Allan Spradling, Director
Department of Embryology, Carnegie Institution for Science
Eggs are uniquely important animal cells. Only eggs can support the development of...
Mitotic proteins take on editorial duties in this writeup of new work from Yixian Zheng's lab in The Journal of Cell Biology....
Cells often face low-oxygen conditions at night. When this happens, some organisms such as the single-cell alga Chlamydomonas are able to generate cellular energy from the breakdown of sugars...
Nutrition and metabolism are closely linked with reproductive health. Several reproductive disorders have been linked to malnutrition, diabetes, and obesity. Furthermore, fasting in numerous species...
Baltimore, MD— Nutrition and metabolism are closely linked with reproductive health. Several reproductive disorders including polycystic ovary syndrome, amenorrhea, and ovarian cancer have been...
Pages
The Spradling laboratory studies the biology of reproduction. By unknown means eggs reset the normally irreversible processes of differentiation and aging. The fruit fly Drosophila provides a favorable multicellular system for molecular genetic studies. The lab focuses on several aspects of egg...
Approximately half of the gene sequences of human and mouse genomes comes from so-called mobile elements—genes that jump around the genome. Much of this DNA is no longer capable of moving, but is likely “auditioning” perhaps as a regulator of gene function or in homologous...
Stem cells make headline news as potential treatments for a variety of diseases. But undertstanding the nuts and bolts of how they develop from an undifferentiated cell that gives rise to cells that are specialized such as organs, or bones, and the nervous system, is not well understood....
Yixian Zheng is Director of the Department of Embryology. Her lab has a long-standing interest in cell division. In recent years, their findings have broadened their research using animal models, to include the study of stem cells, genome organization, and lineage specification—how stem cells...
Frederick Tan holds a unique position at Embryology in this era of high-throughput sequencing where determining DNA and RNA sequences has become one of the most powerful technologies in biology. DNA provides the basic code shared by all our cells to program our development. While there are about 30...
The mouse is a traditional model organism for understanding physiological processes in humans. Chen-Ming Fan uses the mouse to study the underlying mechanisms involved in human development and genetic diseases. He concentrates on identifying and understanding the signals that direct the...
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The Pew Charitable Trust has awarded Carnegie’s Steve Farber and colleague John F. Rawls of Duke University a $200,000 grant to investigate how dietary nutrients, such as fats, alter the...
Almost half of our DNA is made up of jumping genes, moving around the genome in developing sperm and egg cells. Given their ability to jump around the genome, their invasion can trigger DNA...
