Genetics & Developmental Biology Stories
Allan Spradling offers input to The Scientist on a paper about female Japanese rice fish producing sperm....
Dr. Matthew P. Scott
President,
Carnegie Institution for Science
Carnegie Astronomy is also part of Carnegie Science and the study of all living species. From ancient single-celled organisms evolved...
A Carnegie Evening Lecture
Dr. Allan Spradling, Director
Department of Embryology, Carnegie Institution for Science
Eggs are uniquely important animal cells. Only eggs can support the development of...
Mitotic proteins take on editorial duties in this writeup of new work from Yixian Zheng's lab in The Journal of Cell Biology....
Cells often face low-oxygen conditions at night. When this happens, some organisms such as the single-cell alga Chlamydomonas are able to generate cellular energy from the breakdown of sugars...
Nutrition and metabolism are closely linked with reproductive health. Several reproductive disorders have been linked to malnutrition, diabetes, and obesity. Furthermore, fasting in numerous species...
Baltimore, MD— Nutrition and metabolism are closely linked with reproductive health. Several reproductive disorders including polycystic ovary syndrome, amenorrhea, and ovarian cancer have been...
Baltimore, MD—The newest member of the staff at the Carnegie Department of Embryology, Junior Investigator Zhao Zhang, received the prestigious Larry Sandler Memorial Award at the 56th Annual...
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The Spradling laboratory studies the biology of reproduction. By unknown means eggs reset the normally irreversible processes of differentiation and aging. The fruit fly Drosophila provides a favorable multicellular system for molecular genetic studies. The lab focuses on several aspects of egg...
The thyroid gland secretes thyroxine (TH), a hormone essential for the growth and development of all vertebrates including humans. To understand TH action, the Donald Brown lab studies one of the most dramatic roles of the hormone, the control of amphibian metamorphosis—the process by which a...
In mammals, most lipids, such as fatty acids and cholesterol, are absorbed into the body via the small intestine. The complexity of the cells and fluids that inhabit this organ make it very difficult to study in a laboratory setting. The goal of the Farber lab is to better understand the cell and...
Staff Associate Kamena Kostova joined the Department of Embryology in November 2018. She studies ribosomes, the factory-like structures inside cells that produce proteins. Scientists have known about ribosome structure, function, and biogenesis for some time. But, a major unanswered question...
The Ludington lab investigates complex ecological dynamics from microbial community interactions using the fruit fly Drosophila melanogaster. The fruit fly gut carries numerous microbial species, which can be cultured in the lab. The goal is to understand the gut ecology...
The first step in gene expression is the formation of an RNA copy of its DNA. This step, called transcription, takes place in the cell nucleus. Transcription requires an enzyme called RNA polymerase to catalyze the synthesis of the RNA from the DNA template. This, in addition to other processing...
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Baltimore, MD--Cells in the body wear down over time and die. In many organs, like the small intestine, adult stem cells play a vital role in maintaining function by replacing old cells with new ones...
Body organs such as the intestine and ovaries undergo structural changes in response to dietary nutrients that can have lasting impacts on metabolism, as well as cancer susceptibility, according to...
We would not expect a baby to join a team or participate in social situations that require sophisticated communication. Yet, most developmental biologists have assumed that young cells, only recently...
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