Stanford, CA—Photosynthesis is probably the most well-known aspect of plant biochemistry. It enables plants, algae, and select bacteria to transform the energy from sunlight during the daytime into...
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Stanford, CA— Proteins are the machinery that accomplishes almost every task in every cell in every living organism. The instructions for how to build each protein are written into a cell’s DNA. But...
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Stanford, CA—When it comes to cellular architecture, function follows form. Plant cells contain a dynamic cytoskeleton which is responsible for directing cell growth, development, movement, and...
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Each year, the journal The Scientist ranks academic research institutions across the US. This year, Plant Biology is among the top 5. We will make every effort to keep this place among the most...
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AudioStanford, CA—Sugars are an essential source of energy for microrganisms, animals, and humans. They are produced by plants, which convert...
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New work has for the first time elucidated the atomic structures of the bacterial prototype of sugar transporters, termed “SWEET” transporters, found in plants and humans. These bacterial sugar...
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AudioStanford, CA—Everyone’s heard of the birds and the bees. But that old expression leaves out the flowers that are being fertilized. The...
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Carnegie will receive Phase II funding through Grand Challenges Explorations, an initiative created by the Bill & Melinda Gates Foundation that enables individuals worldwide to test bold ideas to address persistent health and development challenges. Department of Plant Biology Director Wolf...
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Today, humanity is increasingly aware of the impact it has on the environment and the difficulties caused when the environment impacts our communities. Environmental change can be particularly harsh when the plants we use for food, fuel, feed and fiber are affected by this change. High salinity is...
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Fresh water constitutes less than 1% of the surface water on earth, yet the importance of this simple molecule to all life forms is immeasurable. Water represents the most vital reagent for chemical reactions occurring in a cell. In plants, water provides the structural support necessary for plant...
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Steroids are important hormones in both animals and plants. They bulk up plants just as they do human athletes, but the pathway of molecular signals that tell the genes to boost growth and development is more complex in plant cells than in animal cells. Unlike animals, plants do not have glands to...
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Matthew Evans wants to provide new tools for plant scientists to engineer better seeds for human needs. He focuses on one of the two phases to their life cycle. In the first phase, the sporophyte is the diploid generation—that is with two similar sets of chromosomes--that undergoes meiosis to...
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It’s common knowledge that light is essential for plants to perform photosynthesis—converting light energy into chemical energy by transforming carbon dioxide and water into sugars for fuel. Plants maximize the process by bending toward the light in a process called phototropism, which is...
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AudioStanford, CA— As every gardner knows, nitrogen is crucial for a plant’s growth. But nitrogen absorption is inefficient. This means that on the scale of food crops, adding significant levels of...
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AudioStanford, CA— Photosynthesis provides fixed carbon and energy for nearly all life on Earth, yet many aspects of this fascinating process remain mysterious. For example, little is known about how...
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Stanford, CA—The Howard Hughes Medical Institute (HHMI) and the Simons Foundation have awarded José Dinneny, of Carnegie’s Department of Plant Biology an HHMI-Simons Faculty Scholar grant. He is one...
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Explore Carnegie Science

February 16, 2018

Stanford, CA—Roots face many challenges in the soil in order to supply the plant with the necessary water and nutrients.  New work from Carnegie and Stanford University’s José Dinneny shows that one of these challenges, salinity, can cause root cells to explode if the risk is not properly sensed. The findings, published by Current Biology, could help scientists improve agricultural productivity in saline soils, which occur across the globe and reduce crop yields.

Salts build up in soils from natural causes, such as sea spray, or can be introduced as a consequence of irrigation and poor land management. Salinity has deleterious effects on plant health and limits crop yields,

Carnegie Science, Carnegie Institution, Carnegie Institution for Science, Stanford University
January 9, 2018

Washington, DC— Without eyes, ears, or a central nervous system, plants can perceive the direction of environmental cues and respond to ensure their survival.

For example, roots need to extend through the maze of nooks and crannies in the soil toward sources of water and nutrients. The various ways that plants guide this branching to take advantage of their environment is of great interest to scientists and of potential use by farmers in need of crops that produce more food with fewer resources.

Carnegie and Stanford University biologist José Dinneny has spent years studying how root growth responds to water, particularly through a phenomenon called hydropatterning, which

October 4, 2017

Science News magazine has selected José Dinneny, of Carnegie’s Department of Plant Biology, as one of ten young scientists to watch in 2017. The researchers were selected because they are likely to make big discoveries. The investigators are spotlighted in the October 14 edition of Science News available online today at www.sciencenews.org/SN10.

Dinneny looks at the mechanisms plants use to sense water availability and survive stressful conditions such as drought and high salinity. He investigates developmental pathways and molecular genetic mechanisms involved in shaping the plant to suit the environment. His work has included the processes of water-stress responses in plants at

Carnegie Science, Carnegie Institution, Carnegie Institution for Science, Donald Danforth Plant Science Center
October 2, 2017

Stanford, CA— Carnegie Plant Biology Acting Director Sue Rhee and staff scientist José Dinneny and their labs are part of a research effort led by The Donald Danforth Plant Science Center, one of the world’s largest independent plant science institutes, which today announced a 5-year, $16 million grant from the U.S. Department of Energy.

Building on earlier research using the often-studied model grass called green foxtail (Setaria viridis), this project will identify new genes and pathways that contribute to photosynthesis and enhanced water-use efficiency. The team will then deploy these genes using tools from the emerging field of synthetic biology to accelerate development of

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Today, humanity is increasingly aware of the impact it has on the environment and the difficulties caused when the environment impacts our communities. Environmental change can be particularly harsh when the plants we use for food, fuel, feed and fiber are affected by this change. High salinity is an agricultural contaminant of increasing significance. Not only does this limit the land available for use in agriculture, but in land that has been used for generations, the combination of irrigation and evaporation gradually leads to increasing soil salinity.

The Dinneny lab focuses on understanding how developmental processes such as cell-type specification regulate responses to

Revolutionary progress in understanding plant biology is being driven through advances in DNA sequencing technology. Carnegie plant scientists have played a key role in the sequencing and genome annotation efforts of the model plant Arabidopsis thaliana and the soil alga Chlamydomonas reinhardtii. Now that many genomes from algae to mosses and trees are publicly available, this information can be mined using bioinformatics to build models to understand gene function and ultimately for designing plants for a wide spectrum of applications.

 Carnegie researchers have pioneered a genome-wide gene association network Aranet that can assign functions to genes for which no function had

Carnegie researchers recently constructed genetically encoded FRET sensors for a variety of important molecules such as glucose and glutamate. The centerpiece of these sensors is a recognition element derived from the superfamily of bacterial binding protiens called periplasmic binding protein (PBPs), proteins that are primary receptors for moving chemicals  for hundreds of different small molecules. PBPs are ideally suited for sensor construction. The scientists fusie individual PBPs with a pair of variants and produced a large set of sensors, e.g. for sugars like maltose, ribose and glucose or for the neurotransmitter glutamate. These sensors have been adopted for measurement of sugar

Fresh water constitutes less than 1% of the surface water on earth, yet the importance of this simple molecule to all life forms is immeasurable. Water represents the most vital reagent for chemical reactions occurring in a cell. In plants, water provides the structural support necessary for plant growth. It acts as the carrier for nutrients absorbed from the soil and transported to the shoot. It also provides the chemical components necessary to generate sugar and biomass from light and carbon dioxide during photosynthesis. While the importance of water to plants is clear, an understanding as to how plants perceive water is limited. Most studies have focused on environmental conditions

It’s common knowledge that light is essential for plants to perform photosynthesis—converting light energy into chemical energy by transforming carbon dioxide and water into sugars for fuel. Plants maximize the process by bending toward the light in a process called phototropism, which is particularly important for germinated seedlings to maximize light capture for growth. Winslow Briggs has been a worldwide leader in unraveling the molecular mechanisms behind this essential plant process.

Over a decade ago Briggs and colleagues discovered and first characterized the photoreceptor family that mediates this directional response and named the two members phototropin 1 and

Arthur Grossman believes that the future of plant science depends on research that spans ecology, physiology, molecular biology and genomics. As such, work in his lab has been extremely diverse. He identifies new functions associated with photosynthetic processes, the mechanisms of coral bleaching and the impact of temperature and light on the bleaching process.

He also has extensively studied the blue-green algae Chlamydomonas genome and is establishing methods for examining the set of RNA molecules and the function of proteins involved in their photosynthesis and acclimation. He also studies the regulation of sulfur metabolism in green algae and plants.  

Grossman and

Wolf Frommer believes that understanding the basic mechanisms of plant life can help us solve problems in agriculture, the environment and medicine, and  even provide understanding of human diseases. He and his colleagues develop fundamental tools and technologies that advance our understanding of glucose, sucrose, ammonium, amino acid, and nucleotide transport in plants.

Transport proteins are responsible for moving materials such as nutrients and metabolic products through a cell’s outer membrane, which seals and protects all living cells, to the cell’s interior. These transported molecules include sugars, which can be used to fuel growth or to respond to chemical signals of

Steroids are important hormones in both animals and plants. They bulk up plants just as they do human athletes, but the pathway of molecular signals that tell the genes to boost growth and development is more complex in plant cells than in animal cells. Unlike animals, plants do not have glands to produce and secrete hormones. Rather, each plant cell has the ability to generate hormones. Another difference is that animal cells typically have receptor molecules that respond to select steroids located within a cell's nucleus. In plants, steroid receptors are anchored to the outside surface of a cell’s outer membrane—the membrane that delineates a cell as a single unit.

Zhiyong Wang