Stanford, CA— An international team of 12 leading plant biologists, including Carnegie’s Wolf Frommer, say their discoveries could have profound implications for increasing the supply of food and...
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Valdivia, Chile, and Washington, D.C.—Cancer cells break down sugars and produce the metabolic acid lactate at a much higher rate than normal cells. This phenomenon provides a telltale sign that...
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Washington, D.C. —Until now it has not been clear how salt, a scourge to agriculture, halts the growth of the plant-root system. A team of researchers, led by the Carnegie Institution’s...
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Stanford, CA — Plants grow upward from a tip of undifferentiated tissue called the shoot apical meristem. As the tip extends, stem cells at the center of the meristem divide and increase in numbers....
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Washington, DC—The Carnegie Institution announced today that it is a grant recipient of the Grand Challenges Explorations initiative funded by the Bill & Melinda Gates Foundation. Wolf B. Frommer...
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Stanford, CA —Light is not only the source of a plant’s energy, but also an environmental signal that instructs the growth behavior of plants. As a result, a plant’s sensitivity to light is of great...
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Stanford, CA—The scientific community needs to make a 10-year, $100 billion investment in food and energy security, says Carnegie’s Wolf Frommer and Tom Brutnell of the Donald Danforth Plant Science...
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Washington, D.C.—The American Society for Plant Biology (ASPB) awarded Wolf B. Frommer, director of Carnegie’s Department of Plant Biology, the Lawrence Bogorad Award for Excellence in Plant Biology...
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Fresh water constitutes less than 1% of the surface water on earth, yet the importance of this simple molecule to all life forms is immeasurable. Water represents the most vital reagent for chemical reactions occurring in a cell. In plants, water provides the structural support necessary for plant...
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Carnegie will receive Phase II funding through Grand Challenges Explorations, an initiative created by the Bill & Melinda Gates Foundation that enables individuals worldwide to test bold ideas to address persistent health and development challenges. Department of Plant Biology Director Wolf...
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Revolutionary progress in understanding plant biology is being driven through advances in DNA sequencing technology. Carnegie plant scientists have played a key role in the sequencing and genome annotation efforts of the model plant Arabidopsis thaliana and the soil alga Chlamydomonas reinhardtii....
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Plants are essential to life on Earth and provide us with food, fuel, clothing, and shelter.  Despite all this, we know very little about how they do what they do. Even for the best-studied species, such as Arabidopsis thaliana --a wild mustard studied in the lab--we know about less than 20% of...
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Arthur Grossman believes that the future of plant science depends on research that spans ecology, physiology, molecular biology and genomics. As such, work in his lab has been extremely diverse. He identifies new functions associated with photosynthetic processes, the mechanisms of coral bleaching...
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One way to adapt to climate change is to understand how plants can thrive in the changing environment. José Dinneny looks at the mechanisms that control environmental responses in plants, including responses to salty soils and different moisture conditions—work that provides the foundation for...
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AudioStanford, CA— Photosynthesis provides fixed carbon and energy for nearly all life on Earth, yet many aspects of this fascinating process remain mysterious. For example, little is known about how...
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Washington, D.C.--Plant Biology postdoctoral research associate since 2012, Jia-Ying Zhu was awarded the sixth PIE award for her creativity, productivity, being a great team player in research, “and...
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Carnegie Plant Biology Acting Director Sue Rhee and staff scientist José Dinneny and their labs are part of a research effort led by The Donald Danforth Plant Science Center, one of the world’s...
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February 16, 2018

Stanford, CA—Roots face many challenges in the soil in order to supply the plant with the necessary water and nutrients.  New work from Carnegie and Stanford University’s José Dinneny shows that one of these challenges, salinity, can cause root cells to explode if the risk is not properly sensed. The findings, published by Current Biology, could help scientists improve agricultural productivity in saline soils, which occur across the globe and reduce crop yields.

Salts build up in soils from natural causes, such as sea spray, or can be introduced as a consequence of irrigation and poor land management. Salinity has deleterious effects on plant health and limits crop yields,

Carnegie Science, Carnegie Institution, Carnegie Institution for Science, Stanford University
January 9, 2018

Washington, DC— Without eyes, ears, or a central nervous system, plants can perceive the direction of environmental cues and respond to ensure their survival.

For example, roots need to extend through the maze of nooks and crannies in the soil toward sources of water and nutrients. The various ways that plants guide this branching to take advantage of their environment is of great interest to scientists and of potential use by farmers in need of crops that produce more food with fewer resources.

Carnegie and Stanford University biologist José Dinneny has spent years studying how root growth responds to water, particularly through a phenomenon called hydropatterning, which

October 4, 2017

Science News magazine has selected José Dinneny, of Carnegie’s Department of Plant Biology, as one of ten young scientists to watch in 2017. The researchers were selected because they are likely to make big discoveries. The investigators are spotlighted in the October 14 edition of Science News available online today at www.sciencenews.org/SN10.

Dinneny looks at the mechanisms plants use to sense water availability and survive stressful conditions such as drought and high salinity. He investigates developmental pathways and molecular genetic mechanisms involved in shaping the plant to suit the environment. His work has included the processes of water-stress responses in plants at

Carnegie Science, Carnegie Institution, Carnegie Institution for Science, Donald Danforth Plant Science Center
October 2, 2017

Stanford, CA— Carnegie Plant Biology Acting Director Sue Rhee and staff scientist José Dinneny and their labs are part of a research effort led by The Donald Danforth Plant Science Center, one of the world’s largest independent plant science institutes, which today announced a 5-year, $16 million grant from the U.S. Department of Energy.

Building on earlier research using the often-studied model grass called green foxtail (Setaria viridis), this project will identify new genes and pathways that contribute to photosynthesis and enhanced water-use efficiency. The team will then deploy these genes using tools from the emerging field of synthetic biology to accelerate development of

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Revolutionary progress in understanding plant biology is being driven through advances in DNA sequencing technology. Carnegie plant scientists have played a key role in the sequencing and genome annotation efforts of the model plant Arabidopsis thaliana and the soil alga Chlamydomonas reinhardtii. Now that many genomes from algae to mosses and trees are publicly available, this information can be mined using bioinformatics to build models to understand gene function and ultimately for designing plants for a wide spectrum of applications.

 Carnegie researchers have pioneered a genome-wide gene association network Aranet that can assign functions to genes for which no function had

Today, humanity is increasingly aware of the impact it has on the environment and the difficulties caused when the environment impacts our communities. Environmental change can be particularly harsh when the plants we use for food, fuel, feed and fiber are affected by this change. High salinity is an agricultural contaminant of increasing significance. Not only does this limit the land available for use in agriculture, but in land that has been used for generations, the combination of irrigation and evaporation gradually leads to increasing soil salinity.

The Dinneny lab focuses on understanding how developmental processes such as cell-type specification regulate responses to

Fresh water constitutes less than 1% of the surface water on earth, yet the importance of this simple molecule to all life forms is immeasurable. Water represents the most vital reagent for chemical reactions occurring in a cell. In plants, water provides the structural support necessary for plant growth. It acts as the carrier for nutrients absorbed from the soil and transported to the shoot. It also provides the chemical components necessary to generate sugar and biomass from light and carbon dioxide during photosynthesis. While the importance of water to plants is clear, an understanding as to how plants perceive water is limited. Most studies have focused on environmental conditions

Carnegie researchers recently constructed genetically encoded FRET sensors for a variety of important molecules such as glucose and glutamate. The centerpiece of these sensors is a recognition element derived from the superfamily of bacterial binding protiens called periplasmic binding protein (PBPs), proteins that are primary receptors for moving chemicals  for hundreds of different small molecules. PBPs are ideally suited for sensor construction. The scientists fusie individual PBPs with a pair of variants and produced a large set of sensors, e.g. for sugars like maltose, ribose and glucose or for the neurotransmitter glutamate. These sensors have been adopted for measurement of sugar

Plants are essential to life on Earth and provide us with food, fuel, clothing, and shelter.  Despite all this, we know very little about how they do what they do. Even for the best-studied species, such as Arabidopsis thaliana --a wild mustard studied in the lab--we know about less than 20% of what its genes do and how or why they do it. And understanding this evolution can help develop new crop strains to adapt to climate change.  

Sue Rhee wants to uncover the molecular mechanisms underlying adaptive traits in plants to understand how these traits evolved. A bottleneck has been the limited understanding of the functions of most plant genes. Rhee’s group is building genome-wide

Plants are not as static as you think. David Ehrhardt combines confocal microscopy with novel visualization methods to see the three-dimensional movement  within live plant cells to reveal the other-worldly cell choreography that makes up plant tissues. These methods allow his group to explore cell-signaling and cell-organizational events as they unfold.

These methods allow his lab to investigate plant cell development and structure and molecular genetics to understand the organization and dynamic behaviors of molecules and organelles. The group tackles how cells generate asymmetries and specific shapes. A current focus is how the cortical microtubule cytoskeleton— an interior

Wolf Frommer believes that understanding the basic mechanisms of plant life can help us solve problems in agriculture, the environment and medicine, and  even provide understanding of human diseases. He and his colleagues develop fundamental tools and technologies that advance our understanding of glucose, sucrose, ammonium, amino acid, and nucleotide transport in plants.

Transport proteins are responsible for moving materials such as nutrients and metabolic products through a cell’s outer membrane, which seals and protects all living cells, to the cell’s interior. These transported molecules include sugars, which can be used to fuel growth or to respond to chemical signals of

Arthur Grossman believes that the future of plant science depends on research that spans ecology, physiology, molecular biology and genomics. As such, work in his lab has been extremely diverse. He identifies new functions associated with photosynthetic processes, the mechanisms of coral bleaching and the impact of temperature and light on the bleaching process.

He also has extensively studied the blue-green algae Chlamydomonas genome and is establishing methods for examining the set of RNA molecules and the function of proteins involved in their photosynthesis and acclimation. He also studies the regulation of sulfur metabolism in green algae and plants.  

Grossman and