Plants are not as static as you think. David Ehrhardt combines confocal microscopy with novel visualization methods to see the three-dimensional movement  within live plant cells to reveal the other-worldly cell choreography that makes up plant tissues. These methods allow his group to explore cell-signaling and cell-organizational events as they unfold.

These methods allow his lab to investigate plant cell development and structure and molecular genetics to understand the organization and dynamic behaviors of molecules and organelles. The group tackles how cells generate asymmetries and specific shapes. A current focus is how the cortical microtubule cytoskeleton— an interior scaffolding that directs construction of the cell’s walls and the growth of the plant—is organized and functions and how this guides patterns of cell growth and division. This scaffolding is crucial for supporting important plant functions such as photosynthesis, nutrient gathering, and reproduction.

Recently, his group provided surprising evidence on how this reorganization process works. The cytoskeleton undergirding in each cell includes an array of tubule-shaped protein fibers called microtubules. The evidence suggests that the direction of a light source influences a plant’s growth pattern.

Imaging data, combined with the results of genetic experiments, revealed a mechanism by which plants orient microtubule arrays. A protein called katanin drives this mechanism, which it achieves by redirecting microtubule growth in response to blue light. It does so by severing the microtubules where they intersect with each other, creating new ends that can regrow and themselves be severed, resulting in a rapid amplification of new microtubules lying in another, more desired, direction.

Ehrhardt  received his Sc. B. from Brown University and his Ph.D. from Stanford University, where he was also a postdoctoral fellow before coming to Carnegie as a staff member. For more see https://dpb.carnegiescience.edu/labs/ehrhardt-lab

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Greenhouse in Germany where Exposito-Alonso did research.
April 10, 2020

Palo Alto, CA— Carnegie’s Moises Exposito-Alonso was selected for the Heidelberg Academy of Science’s Karl Freudenberg Prize in recognition of outstanding early career achievements in the natural sciences. The prize comes with a personal 10,000 Euro award.

Representing the German state of Baden-Württemberg, the academy honors several professors under the age of 40 with endowed prizes each year, including six in 2020. All of the recipients will give public presentations of their work, with dates to be announced. An evolutionary geneticist, Exposito-Alonso received his doctorate in 2018 from the Max Planck Institute for Developmental Biology in Tübigen.

Moises Exposito-Alonso
March 18, 2020

Washington, DC— Carnegie evolutionary geneticist Moises Exposito-Alonso was named a member of the 2020 class of Forbes’ 30 Under 30 Europe list in science and healthcare. 

He was recognized for his lab’s pioneering use of genomic techniques to understand how plant species will evolve and keep pace with a changing climate. 

Out of the thousands of nominees, the 30 finalists in each of the 10 categories comprise “the world’s most impactful community of young entrepreneurs and game-changers,” said the publication in announcing his selection.  

“Growing up in southern Spain, I saw how Mediterranean

Caltech logo
March 17, 2020

The Carnegie Institution for Science is consolidating our California research departments into an expanded presence in Pasadena. With this move, we are building on our existing relationship with Caltech, with a goal of broadening our historic collaborations in astronomy and astrophysics and pursuing new opportunities in ecology and plant biology that will support the global fight against climate change.

This plan, which affects our research operations in Pasadena and Palo Alto, reflects Carnegie’s ongoing efforts to extend our leadership in space, Earth, and life sciences and to enhance our ability to explore new frontiers.

In selecting our Pasadena location, we

Moises Exposito-Alonso
February 28, 2020

Palo Alto, CA— Carnegie’s Moises Exposito-Alonso is one of four recipients of the American Society of Naturalists’ Jasper Loftus-Hills Young Investigator Award in recognition of “outstanding and promising work” by individuals who are within three years of completing their Ph.D or in their final year of graduate school.

Exposito-Alonso is an evolutionary geneticist who joined Carnegie last September as a staff associate, a prestigious position designed for early career scientists who are ready to independently deploy creative approaches to challenging research projects. 

His lab is pioneering the use of genomics to ask whether species will

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Revolutionary progress in understanding plant biology is being driven through advances in DNA sequencing technology. Carnegie plant scientists have played a key role in the sequencing and genome annotation efforts of the model plant Arabidopsis thaliana and the soil alga Chlamydomonas reinhardtii. Now that many genomes from algae to mosses and trees are publicly available, this information can be mined using bioinformatics to build models to understand gene function and ultimately for designing plants for a wide spectrum of applications.

 Carnegie researchers have pioneered a genome-wide gene association network Aranet that can assign functions

Evolutionary geneticist Moises Exposito-Alonso joined the Department of Plant Biology as a staff associate in September 2019. He investigates whether and how plants will evolve to keep pace with climate change by conducting large-scale ecological and genome sequencing experiments. He also develops computational methods to derive fundamental principles of evolution, such as how fast natural populations acquire new mutations and how past climates shaped continental-scale biodiversity patterns. His goal is to use these first principles and computational approaches to forecast evolutionary outcomes of populations under climate change to anticipate potential future

Staff Associate Kamena Kostova joined the Department of Embryology in November 2018. She studies ribosomes, the factory-like structures inside cells that produce proteins. Scientists have known about ribosome structure, function, and biogenesis for some time. But, a major unanswered question is how cells monitor the integrity of the ribosome itself. Problems with ribosomes have been associated with diseases including neurodegeneration and cancer. The Kostova lab investigates the fundamental question of how cells respond when their ribosomes break down using mass spectrometry, functional genomics methods, and CRISPR genome editing.

Kostova received a B.S. in Biology from the

Sally June Tracy applies cutting-edge experimental and analytical techniques to understand the fundamental physical behavior of materials at extreme conditions. She uses dynamic compression techniques with high-flux X-ray sources to probe the structural changes and phase transitions in materials at conditions that mimic impacts and the interiors of terrestrial and exoplanets. She is also an expert in nuclear resonant scattering and synchrotron X-ray diffraction. She uses these techniques to understand novel behavior at the electronic level.  Tracy received her Ph.D. from the California Institute of

The Ludington lab investigates complex ecological dynamics from microbial community interactions using the fruit fly  Drosophila melanogaster. The fruit fly gut carries numerous microbial species, which can be cultured in the lab. The goal is to understand the gut ecology and how it relates to host health, among other questions, by taking advantage of the fast time-scale and ease of studying the fruit fly in controlled experiments.